A compendium of natural philosophical knowledge, written in 1718-1720 by John Questebrune, chaplain to the 6th Earl of Galway. The chapters treat the various parts of the physical world (earth, water, air, and fire), plants (including a great deal on medicinal plants), animals, and the human body and soul. The volume is embellished with decorative chapter headings and pen and ink and watercolor sketches depicting the terrestrial globe, the Ptolemaic and Copernican solar systems, the phases of the moon, and the human body in dissection.

Founded in 1743 by Benjamin Franklin, the American Philosophical Society was the first learned society in the United States. For over 250 years, the Society has played an important role in American cultural and intellectual life. Until the mid-nineteenth century, the Society fulfilled the role of a national academy of science, national library and museum, and even patent office. Early members of the Society included Thomas Jefferson, David Rittenhouse, Benjamin Rush, Stephen Peter Du Ponceau, George Washington, and many other figures prominent in American history. The Archives of the American Philosophical Society consists of 192.25 linear feet of material, organized into thirteen record groups dating back to 1743. The Society's archives extensively documents not only the organization's historical development but also its role in American history and the history of science and technology.